The aim is to analyse gender-specific aspects in the EARCO cohort. To this end, cross-sectional analyses of all patients for whom information on gender is available are planned. The following questions are to be answered
1) Are there differences between men and women in terms of awareness of AATD, time of diagnosis, functional limitations at initial diagnosis, referral to a specialist, diagnostic work-up (lung function, CT chest, elastography, etc.) and initiation of augmentation therapy?
2) Are there gender differences in symptoms, frequency and severity of exacerbations, risk factors such as tobacco, alcohol and exposure? The extent and characteristics of lung disease (asthma, COPD, bronchiectasis) and the pattern of comorbidities?