• To identify ZZ patients who present with a primary diagnosis of Bronchiectasis and little or no emphysema.
• To determine any differences in presentation and management compared to Patients with a primary diagnosis of COPD and Emphysema.
Adult patients (over 18 years of age) with AATD (PiZZ, PiSZ and other rare variants with AAT level <11micromolar) who have been identified by their national / regional AATD centre as having bronchiectasis
Data will be sourced from routine clinical records. There will be no study visits or investigations performed. Anonymised clinical data will be entered into an electronic Case Report Form.
Data will be obtained from assessments obtained as part of routine clinical management. No follow-up will be conducted.